Jamal Keyes has joined the group as a RiSE/REU in Cellular Bioengineering program participant. He will be working on the formulation of antimicrobial peptides using our Graplon copolymers for wound healing applications.
Margot Zevon successfully defended her Ph.D. dissertation entitled, “SWIR Emitting Rare Earth Albumin Nanocomposites for Targeted Imaging, Molecular Phenotyping, and Improved Drug Delivery to Tumors.” Margot was co-advised by Charlie Roth and Prabhas Moghe and will be moving on to a postdoctoral position in pharmacology with Merck.
A patent entitled "Amphiphilic Macromolecules for Nucleic Acid Delivery" was issued recently to Professors Kathryn Uhrich (CCB), Charles Roth (BME/CBE), along with former Ph.D. students Sarah Sparks, Alex Harmon, Li Gu (all CCB) and Carolyn Federici (CBE). The invention is based on the design and synthesis of novel macromolecular architectures with tunable domains for sequestration of nucleic acids and for cellular entry.
A patent entitled "Graft Polymers for Enhanced Intracellular Delivery of Antisense Molecules" was issued to Professors Charles Roth (BME/CBE) and David Devore (NJ Center for Biomaterials). The invention is based on the development of a graft copolymer that protects antisense oligonucleotides from systemic degradation, mediates their entry into cells, and reroutes them within cells to their targets. Applications in cancer and w...